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Pharnorcia Inc.

ABOUT PHARNORCIA

Raw materials for Silicone Hydrogel Contact lenses and
Monomers for foldable intraocular lenses (IOL)

WELCOME TO PHARNORCIA company overview

The comprehensive platform of high purity optical grade materials and biomaterials for Silicone Hydrogel Contact lens and Intraocular Lens (IOL)  for about 10 years.

Track records for quality and delivery on time, on budget.

Top experts in R&D, manufacture and cGMP compliance environments from US and China.

Manufacture in compliance with regulatory requirements.

Quality control and standard procedures are implemented and enforced in every aspect of the business.

R&D facilities equipped with or have direct access to NMR, HPLC, GC LC-MS, GC-MS, FTIR, KF etc.

Thin film evaporator system with power of high vacuum range to 0.001 Torr.

PROCUCTION CAPACITY The Professional Support of Pharmaceuticals and Biomaterials
    Research & Development

    More than 200 Chemists and Engineers are working together for timely completion of small-scale and large-scale projects. Laboratories are equipped with or have direct access to NMR, HPLC, GC, LC-MS, GC-MS, FTIR, KF, etc for process research and development, in-process monitoring, and quality assurance.

    Facilities

    Production base of Pharnorcia covers an area of 31.2 acre. More than 800,000 sqft are well established for research laboratories, kilo-labs and pilot plant. The kilo-labs and pilot plant are well equipped with glass jacketed reactors and stainless steel reactors ranging from 1 L to 1000 L, 8 L and 20 L high pressure reactors, 20 L rotary evaporators, and a range of filters. Process chiller manifolds allow quick and precise temperature adjustments. Operating temperatures range from -80°C to 300°C and pressures range from 0.001 torr up to 20 atm.

    Analytical and Quality Control

    Analytical procedures are developed for all custom synthesis projects, unless it is offered and transferred by customer. Our quality control team performs a broad range of analytical testing in compliance with regulatory requirements. Standard operation procedures (SOP) are implemented and enforced for every aspect of the business.

    Process Capabilities
    Process Services
    Acid chlorides
    Acrylation
    Alkoxylation
    Bromination
    Benzenoid reactions
    Benzyl protection
    Carbohydrate chemistry
    Carboxylation
    Chlorination
    Chloromethylation
    Chlorosulfonation
    Condensation
    Cyclization
    Diazotization
    Dimethyl sulphate reactions
    Esterification
    Etherification
    Fluorination
    Formylation
    Halogenation
    hydrogenation
    hydrogenolysis
    Hydroxylation
    Nitration
    Oxidation/Reduction
    Phosgenation
    Ring closure
    Sulfonation
    Thiophosgenation
    Named Reaction
    Claisen condensation
    Dieckmann cyclization
    Diels-Alder
    Fries rearrangement
    Gabriel synthesis
    Gomberg-Bachmann reaction
    Grignard addition
    Hoffman degradation
    Hofmann's reaction
    Mannich reaction
    Michael addition
    Reformatsky reaction
    Ritter reaction
    Rosenmund reduction
    Rosenmund reduction
    Sandmeyer reaction
    Schiff base reduction
    Schotten-Baumann reaction
    Skraup synthesis
    Ullman reaction
    Vilsmeier-Haack reactions
    Wilgerodt reaction
    Williamson synthesis
    Wittig reaction
    Doebner-Knoevenagel condensation
    Friedel-Crafts reaction
  • Research & Development
  • Facilities
  • Analytical and Quality Control
  • Process Capabilities
TRADE CAPACITY

With expertise in organic synthesis, catalysis, pharmaceutical synthesis, biochemistry, carbohydrate and
chemical glycobiology, our scientists offer a full range of services to meet the varying needs of our customers.

  • Custom Synthesis of Milligram to Kilogram Quantities
    Custom Synthesis of Milligram to Kilogram Quantities

    We have a proven track record of preparing a wide range of compounds on a wide range of scales. As your requirements expand, our scientists meet your needs in a timely and cost-effective manner. Since the initial synthesis of preparing a small amount may not meet your expanded target,we will adapt and adopt a synthesis that makes the best fit for your needs and expectations.

  • Scale-up of Existing Processes
    Scale-up of Existing Processes

    If you have already a demonstrated process and need it reproduced, we will meet or exceed your expectations in a timely and efficient manner. Along the way, we will identify and develop steps as appropriate for scale up or safety considerations.

    Separation and Purification Services

    We work for you to identify and develop practical purification strategies for chemical purification or control of polymorphism of crystalline compounds.

  • Process Development, Optimization and Contract Manufacturing
    Process Development, Optimization and Contract Manufacturing

    We develop new and proprietary process of multi-step synthesis. We will also develop an existing synthesis into a scalable process with our in-house talent and state-of-the-art technology. Our scientists have experience developing and transferring projects from research laboratories to kilo-lab to pilot plant. Once your project reaches commercializing level, we can offer cGMP manufacturing facilities. Your projects will benefit from seamless technology transfer.

  • Outsourcing
    Outsourcing

    We have compiled and audited a large database of US and China fine chemical suppliers with proven track records in the quality and lead-time of their products.
    When you want to source raw materials, intermediates or APIs beyond our product lists, our staff can also assist you to find reputable and qualified suppliers. Upon request, we can handle the search, purchase and shipping process for you in a timely and cost-effective manner.

Copyright © 2016 Pharnorcia Inc.

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